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The Research


 Peer-Reviewed, Published Studies and Counting

We engage in rigorous scientific research and testing of all of its ingredients to ensure the most stable, efficacious probiotic finished products available. Here you’ll find links to published probiotic clinical studies on GanedenBC30.

GanedenBC30 cell wall and metabolites: anti–inflammatory and immune modulating effects in vitro

BMC Immunology 2010, 11:15

Gitte S Jensen, Kathleen F Benson, Steve G Carter and John R Endres


In multiple validated lab models, testing demonstrated that GanedenBC30, (both cells walls and supernatant) supports immune health.   

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A controlled clinical trial to evaluate the effect of GanedenBC30 on immunological markers

Methods and Findings in Experimental and Clinical Pharmacology 2010, 32(2): 129-132

M. Kimmel, D. Keller, S. Farmer, and D.E. Warrino


A controlled trial that GanedenBC30 supports immune health by increasing immune response to multiple viral challenges. 

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Bacillus coagulans: A viable adjunct therapy for relieving symptoms of rheumatoid arthritis according to a randomized, controlled trial.

BMC Complementary and Alternative Medicine 2010, 10:1

David R Mandel, Katy Eichas, and Judith Holmes1


A randomized, double blind, placebo-controlled trial that GanedenBC30 improved pain symptoms and increased mobility in subjects with Rheumatoid Arthritis. 

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A prospective, randomized, double–blind, placebo–controlled parallel–group dual site trial to evaluate the effects of a Bacillus coagulans–based product on functional intestinal gas symptoms

BMC Gastroenterology, 2009, 9:85

Douglas S Kalman, Howard I Schwartz, Patricia Alvarez, Samantha Feldman, John C Pezzullo and Diane R Krieger


A randomized, double blind, placebo-controlled trial that GanedenBC30 supports digestive health by reducing abdominal pain and distention in subjects with postprandial gas related symptoms. 

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Survival and metabolic activity of the GanedenBC30 strain of Bacillus coagulans in a dynamic in vitro model of the stomach and small intestine

Beneficial Microbes, 2010; 1(1): 31–36

A.J.H Maathuis, D. Keller, and S. Farmer


A validated stomach and small intestinal model that demonstrated GanedenBC30 supports digestive health by increasing the digestion of proteins and lactose. 

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Effects of a proprietary Bacillus coagulans preparation on symptoms of diarrhea–predominant irritable bowel syndrome

Methods Find Exp Clin Pharmacol 2009; 31(10): 655–659

B.J. Dolin


A randomized, double blind, placebo-controlled trial that GanedenBC30 supports digestive health by reducing the number of bowel movements per day in subjects with IBS-D.

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Ganeden is a science focused organization dedicated to bringing superior probiotics to markets that have been otherwise unmet by traditional solutions.

All Ganeden ingredients are made in the United States of America.